Gall Bladder Cancer

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What is Gallbladder Cancer?

Gallbladder cancer is a rare but aggressive form of cancer that begins in the gallbladder, a small organ located beneath the liver. The gallbladder stores bile, a digestive fluid produced by the liver. Because gallbladder cancer often causes no symptoms in its early stages, it is frequently diagnosed at a more advanced stage.

Causes and Risk Factors

The exact cause of gallbladder cancer is unknown, but several risk factors are associated with its development:

  • • Gallstones: Chronic inflammation from gallstones is a major risk factor.
  • • Gallbladder Polyps: Growths in the gallbladder can sometimes become cancerous.
  • • Chronic Inflammation: Conditions like chronic cholecystitis (inflammation of the gallbladder) increase risk.
  • • Age and Gender: More common in people over 60 and in women.
  • • Family History: A family history of gallbladder cancer can increase risk.

Symptoms Gallbladder cancer often does not cause symptoms until it has progressed. When symptoms do appear, they may include:

  • • Abdominal Pain: Particularly in the upper right side.
  • • Jaundice: Yellowing of the skin and eyes.
  • • Nausea and Vomiting
  • • Unexplained Weight Loss
  • • Lumps in the Abdomen
Diagnosis

Gallbladder cancer is typically diagnosed through a combination of imaging tests, such as ultrasound, CT scans, or MRI, and sometimes a biopsy, where a sample of tissue is taken for analysis. Blood tests may also be used to check liver function and detect cancer markers.

Treatment

Treatment options depend on the stage of the cancer and may include:

  • • Surgery: Removal of the gallbladder (cholecystectomy) and surrounding tissues if the cancer is caught early.
  • • Chemotherapy: Using drugs to kill cancer cells, often used when the cancer has spread.
  • • Radiation Therapy: To shrink tumors or relieve symptoms.
  • • Palliative Care: To manage symptoms and improve quality of life in advanced stages.
Prognosis

The prognosis for gallbladder cancer depends on the stage at diagnosis. Early-stage gallbladder cancer has a better outlook, but because the disease is often detected late, the overall prognosis is typically poor. Early detection and treatment are key to improving outcomes.